Potassium 1,2-naphthoquinone-4-sulphonate

Potassium 1,2-naphthoquinone-4-sulphonate (Compound 16) is a 6-phosphogluconate dehydrogenase (6PGDH) inhibitor with an IC50 of 53 μM. Potassium 1,2-naphthoquinone-4-sulphonate can be used in the study of human African trypanosomiasis[1].

Product Specifications

CAS Number

[5908-27-0]

UNSPSC

12352005

Hazard Statement

H319, H335

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Infection

Purity

99.79

Smiles

O=C1C=C(S(=O)(O[K])=O)C2=CC=CC=C2C1=O

Molecular Formula

C10H5KO5S

Molecular Weight

276.31

Precautions

H319, H335

References & Citations

[1]Ruda GF, et al. Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase. Bioorg Med Chem. 2010 Jul 15;18 (14) :5056-62.