Epibestatin (hydrochloride)

Epibestatin hydrochloride is a protease inhibitor. Epibestatin stabilizes the 14-3-3/PMA2 complex. Epibestatin hydrochloride can be used in the research of cancer[1][2].

Product Specifications

CAS Number

[100992-60-7]

UNSPSC

12352005

Target

Molecular Glues

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@H](O)[C@H](N)CC1=CC=CC=C1)=O.Cl

Molecular Formula

C16H25ClN2O4

Molecular Weight

344.83

References & Citations

[1]Richter A, et al. A practical and convenient synthesis of the protease inhibitor epibestatin. Synthesis, 2010, 2010 (12) : 2039-2042. |[2]Ottmann C. Cover Picture: Identification and Structure of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions (Angew. Chem. Int. Ed. 24/2010) [J]. Angewandte Chemie International Edition, 2010.