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MFZ 2-13

MFZ 2-13 (O-456) is an N-demethylated intermediate and N-nor-analogue of MFD 2-12. MFZ 2-13 inhibits dopamine uptake through the human dopamine receptor with an IC50 of 1.4 nM[1].

Product Specifications

CAS Number

146725-34-0

Product Name Alternative

O-456

UNSPSC

12352005

Target

Dopamine Receptor; Drug Intermediate

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease

Smiles

COC([C@H]1[C@@H](C2=CC(Cl)=C(C=C2)Cl)C[C@@]3([H])N[C@]1([H])CC3)=O

Molecular Formula

C15H17Cl2NO2

Molecular Weight

314.21

References & Citations

[1]Newman, A. H., et al., (2001) . [3H]MFZ 2-12: a novel radioligand for the dopamine transporter. Bioorganic & medicinal chemistry letters, 11 (13), 1659–1661.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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