Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

(S,R,S)-AHPC-PEG4-N3

Product Specifications

UNSPSC Description

(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/E3_ligase_Ligand-Linker_Conjugates_4.html

Purity

99.93

Solubility

DMSO : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCOCCN=[N+]=[N-]

Molecular Weight

689.82

References & Citations

[1]Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chemical Biology (2015), 10(8), 1770-1777.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-103601/S-R-S-AHPC-PEG4-N3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-103601/S-R-S-AHPC-PEG4-N3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1797406-81-5

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Triethyloxonium hexafluorophosphate
T22412-01 5 g

Triethyloxonium hexafluorophosphate

Ask
View Details
Triethyloxonium hexafluorophosphate
T22412-02 25 g

Triethyloxonium hexafluorophosphate

Ask
View Details
GPR14 (UTS2R) (NM_018949) Human Tagged ORF Clone
RG228005 10 µg

GPR14 (UTS2R) (NM_018949) Human Tagged ORF Clone

Ask
View Details
CHMP4A ORF Vector (Human) (pORF)
16086011 1.0 µg DNA

CHMP4A ORF Vector (Human) (pORF)

Ask
View Details
PTL-21-427-GY AF Systems Consumables
018514 Roll of 100 Label(s)

PTL-21-427-GY AF Systems Consumables

Ask
View Details
TMEM85 Lentiviral Activation Particles (h2)
sc-412153-LAC-2 200 µL

TMEM85 Lentiviral Activation Particles (h2)

Ask
View Details