VR23-d8
VR23-d8 is the deuterium labeled VR23 (HY-18741) . VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM) .
Product Specifications
CAS Number
[2733154-83-9]
UNSPSC
12352005
Target
Apoptosis; Isotope-Labeled Compounds; Proteasome
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
ClC1=CC2=C(C(N3C([2H])(C([2H])(N(C([2H])(C3([2H])[2H])[2H])S(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)(=O)=O)[2H])[2H])=CC=N2)C=C1
Molecular Formula
C19H8D8ClN5O6S
Molecular Weight
485.93
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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