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VR23-d8

VR23-d8 is the deuterium labeled VR23. VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM).

Product Specifications

CAS Number

2733154-83-9

UNSPSC

12352005

Target

Apoptosis; Isotope-Labeled Compounds; Proteasome

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

ClC1=CC2=C(C(N3C([2H])(C([2H])(N(C([2H])(C3([2H])[2H])[2H])S(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)(=O)=O)[2H])[2H])=CC=N2)C=C1

Molecular Formula

C19H8D8ClN5O6S

Molecular Weight

485.93

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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