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1,6-Di-O-galloyl-β-D-glucose

1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. 1,6-Di-O-galloyl-β-D-glucose has HIV-1 reverse transcriptase (RT) inhibitory activity with an IC50 value of 270 μM. The inhibitory mechanism of 1,6-Di-O-galloyl-β-D-glucose is competitive inhibition of the template primer and non-competitive inhibition of the substrate (dTTP) . 1,6-Di-O-galloyl-β-D-glucose can be used in anti-HIV research[1].

Product Specifications

CAS Number

[23363-08-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Field of Research

Infection

Purity

90.0

Smiles

O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)COC(C3=CC(O)=C(C(O)=C3)O)=O

Molecular Formula

C20H20O14

Molecular Weight

484.36

Precautions

H302, H315, H319, H335

References & Citations

[1]el-Mekkawy S, et al. Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase. Chem Pharm Bull (Tokyo) . 1995 Apr;43 (4) :641-8.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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