N-Desethyl-N-methyl vardenafil
N-Desethyl-N-methyl vardenafil (Demethyl-vardenafil), an analog of Vardenafil , is a PDE5 inhibitor with an IC50 value of 0.14 μM[1].
Product Specifications
CAS Number
224785-87-9
Product Name Alternative
Demethyl-vardenafil
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
CCOC(C=CC(S(N1CCN(CC1)C)(=O)=O)=C2)=C2C3=NC(C4=C(N=C(N4N3)CCC)C)=O
Molecular Formula
C22H30N6O4S
Molecular Weight
474.58
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Corbin J D, et al. Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5) [J]. Neurochemistry international, 2004, 45 (6) : 859-863.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5
Available Sizes
Frequently Asked Questions
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