(4-Aminobenzoyl) -D-glutamic acid

(4-Aminobenzoyl) -D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against H2-pteroate synthesis system, which affects the synthesis of folate, thereby inhibiting growth of bacteria[1].

Product Specifications

CAS Number

[5959-18-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Bacterial; Folate Receptor (FR)

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Smiles

OC(CC[C@H](C(O)=O)NC(C1=CC=C(C=C1)N)=O)=O

Molecular Formula

C12H14N2O5

Molecular Weight

266.25

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Thijssen HH. P-Aminobenzoic acid derivatives as inhibitors of the cell-free H2-pteroate synthesizing system of Escherichia coli. J Med Chem. 1977 Feb;20 (2) :233-6.