(4-Aminobenzoyl) -D-glutamic acid
(4-Aminobenzoyl) -D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against H2-pteroate synthesis system, which affects the synthesis of folate, thereby inhibiting growth of bacteria[1].
Product Specifications
CAS Number
[5959-18-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Bacterial; Folate Receptor (FR)
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
OC(CC[C@H](C(O)=O)NC(C1=CC=C(C=C1)N)=O)=O
Molecular Formula
C12H14N2O5
Molecular Weight
266.25
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Thijssen HH. P-Aminobenzoic acid derivatives as inhibitors of the cell-free H2-pteroate synthesizing system of Escherichia coli. J Med Chem. 1977 Feb;20 (2) :233-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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