Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Benzamide-d5

Benzamide-d5 (Benzenecarboxamide-d5) is deuterium labeled Benzamide. Benzamide (Benzenecarboxamide) is a potent poly (ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH) -induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].

Product Specifications

CAS Number

1235489-47-0

Product Name Alternative

Benzenecarboxamide-d5; Phenylamide-d5

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds; PARP

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

O=C(N)C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]

Molecular Formula

C7H2D5NO

Molecular Weight

126.17

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Cosi C, et al. Benzamide, an inhibitor of poly (ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996 Oct 7;735 (2) :343-8.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

3-Amino-2,7-naphthalenedisulfonic Acid Sodium Salt
TRC-A610265-25G 25 g

3-Amino-2,7-naphthalenedisulfonic Acid Sodium Salt

Sign In for Pricing
View Details
ZNF572 Human Gene Knockout Kit (CRISPR)
KN424676 1 Kit

ZNF572 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Recombinant Granulin Antibody
RC-6648-01 50 μL

Recombinant Granulin Antibody

Sign In for Pricing
View Details
Recombinant Granulin Antibody
RC-6648-02 100 µL

Recombinant Granulin Antibody

Sign In for Pricing
View Details
Recombinant Granulin Antibody
RC-6648-03 1 mL

Recombinant Granulin Antibody

Sign In for Pricing
View Details
HAND2 (C-term) Rabbit Polyclonal Antibody
AP13080PU-N 400 µL

HAND2 (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details