Quifenadine-d10

Quifenadine-d10 is the deuterium labeled Quifenadine (HY-122761) . Quifenadine (Compound 3a), the hydroxyl- (diphenyl) methyl quinuclidine derivative, is a M3 receptor antagonist with an IC50 value > 1000 nM. Quifenadine can be used for the research of neurological disease[1].

Product Specifications

CAS Number

[2470130-17-5]

UNSPSC

12352005

Target

Isotope-Labeled Compounds; mAChR

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

OC(C1=C(C([2H])=C(C([2H])=C1[2H])[2H])[2H])(C2CN3CCC2CC3)C4=C(C([2H])=C(C([2H])=C4[2H])[2H])[2H]

Molecular Formula

C20H13D10NO

Molecular Weight

303.46

References & Citations

[1]Lainé DI, et al. Discovery of novel 1-azoniabicyclo[2.2.2]octane muscarinic acetylcholine receptor antagonists. J Med Chem. 2009 Apr 23;52 (8) :2493-505.