Lercanidipine-d3
Lercanidipine-d3 is the deuterium labeled Lercanidipine (HY-B0612) . Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM) . Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research[1][2][3][4][5].
Product Specifications
CAS Number
[1190043-34-5]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Neurological Disease
Smiles
O=C(C1=C(NC(C)=C(C1C2=CC=CC([N+]([O-])=O)=C2)C(OC)=O)C)OC(C)(CN(CCC(C3=CC=CC=C3)C4=CC=CC=C4)C([2H])([2H])[2H])C
Molecular Formula
C36H38D3N3O6
Molecular Weight
614.75
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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