Rimeporide-15N3 (hydrochloride)
Rimeporide-15N3 (hydrochloride) (EMD-87580-15N3 (hydrochloride) ) is 15N labeled Rimeporide hydrochloride. Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1) .
Product Specifications
Product Name Alternative
EMD-87580-15N3 (hydrochloride)
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Na+/H+ Exchanger (NHE)
Related Pathways
Membrane Transporter/Ion Channel; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=S(C1=C(C=C(C(C([15NH]C([15NH2])=[15NH])=O)=C1)C)S(=O)(C)=O)(C)=O.Cl
Molecular Formula
C11H16Cl 15N3O5S2
Molecular Weight
372.83
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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