Dabigatran etexilate-d11

Dabigatran etexilate-d11 (BIBR 1048-d11) is the deuterium labeled Dabigatran etexilate (HY-10274) . Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin) . Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].

Product Specifications

CAS Number

[2469006-94-6]

Product Name Alternative

BIBR 1048-d11

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Thrombin

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Smiles

O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C=C4)C(NC(OCC([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])=O)=N)=C2

Molecular Formula

C34H30D11N7O5

Molecular Weight

638.80

References & Citations

[1]Blair HA, Keating GM. Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation. Drugs. 2017;77 (3) :331-344. |[2]Wienen W, et al. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally activeprodrug, dabigatran etexilate. Thromb Haemost. 2007 Jul;98 (1) :155-62.