(Z) -Entacapone-d10-1

(Z) -Entacapone-d10-1 is the deuterium labeled (Z) -Entacapone (HY-139089) . (Z) -Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone (HY-14280) . It is also a potential impurity found in commercial preparations of Entacapone and a degradant of Entacapone formed by UV light exposure.

Product Specifications

CAS Number

[1185241-19-3]

UNSPSC

12352005

Target

COMT; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Smiles

OC1=C(C([N+]([O-])=O)=CC(/C=C(C(N(C(C([2H])([2H])[2H])([2H])[2H])C(C([2H])([2H])[2H])([2H])[2H])=O)/C#N)=C1)O

Molecular Formula

C14H5D10N3O5

Molecular Weight

315.35

References & Citations

[1]Wikberg, et al. Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans. Drug Metab. Dispos. 21 (1), 81-92 (1993) .