D-myo-Inositol-1,4,5,6-tetraphosphate (tetrasodium)
Selected Variant
HY-W703190A
Size: 1 Each
D-myo-Inositol-1,4,5,6-tetraphosphate tetrasodium (D-Ins (1,4,5,6) P4 tetrasodium) is one of several different inositol oligophosphate isomers implicated in signal transduction. It almost completely inhibits calcium-activated chloride channels at a concentration of 8-10 μM [1].
Product Specifications
Product Name Alternative
Inositol 1,4,5,6-tetraphosphate (tetrasodium) ; D-Ins (1,4,5,6) P4 (tetrasodium)
UNSPSC
12352211
Target
Chloride Channel; Drug Isomer
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease
Smiles
O[C@H]1[C@@H]([C@H]([C@@H]([C@H]([C@H]1O)OP(O)(O[Na])=O)OP(O)(O[Na])=O)OP(O)(O[Na])=O)OP(O)(O[Na])=O
Molecular Formula
C6H12Na4O18P4
Molecular Weight
588.00
References & Citations
[1]Yang X, et al. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate. J Biol Chem. 1999 Jul 2;274 (27) :18973-80.|[2]Xie W, et al. Inositol 3,4,5,6-tetrakisphosphate inhibits the calmodulin-dependent protein kinase II-activated chloride conductance in T84 colonic epithelial cells. J Biol Chem. 1996 Jun 14;271 (24) :14092-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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