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2-Methyl estradiol

2-Methyl estradiol, an endogenous metabolite of Estradiol , inhibits cell proliferation and angiogenesis, with IC50 values of 3 and 2.39 μM for HUVEC and MCF-7 human breast cancer cell proliferation, respectively[1].

Product Specifications

CAS Number

1818-12-8

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(C)=C(O)C=C4CC3

Molecular Formula

C19H26O2

Molecular Weight

286.41

References & Citations

[1]Iljung Lee, et al. 2-[methyl- (11) C]methoxyestradiol: synthesis, evaluation and pharmacokinetics for in vivo studies on angiogenesis. Nucl Med Biol. 2007 Aug;34 (6) :625-31.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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