Fenhexamid-d10

Fenhexamid-d10 is the deuterium labeled Fenhexamid (HY-118065) . Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) [1].

Product Specifications

CAS Number

[1246815-53-1]

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Fungal; Isotope-Labeled Compounds; PI3K

Related Pathways

Anti-infection; Others; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

OC1=CC=C(C(Cl)=C1Cl)NC(C2(C([2H])(C([2H])(C([2H])(C([2H])(C2([2H])[2H])[2H])[2H])[2H])[2H])C)=O

Molecular Formula

C14H7D10Cl2NO2

Molecular Weight

312.26

References & Citations

[1]Debieu D, et al. The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) . Pest Manag Sci. 2001 Nov;57 (11) :1060-7.|[2]Go RE, et al., Effect of fenhexamid and cyprodinil on the expression of cell cycle- and metastasis-related genes via an estrogen receptor-dependent pathway in cellular and xenografted ovarian cancer models. Toxicol Appl Pharmacol. 2015 Nov 15;289 (1) :48-57.|[3]Medjakovic S, et al., Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. Environ Toxicol. 2014 Oct;29 (10) :1201-16.|[4]Go RE, et al., A fungicide, fenhexamid, is involved in the migration and angiogenesis in breast cancer cells expressing estrogen receptors. Life Sci. 2022 Sep 15;305:120754.