3,4-Dihydroxyamphetamine (hydrochloride)
3,4-Dihydroxyamphetamine (α-Methyldopamine) (hydrochloride) is a secondary metabolite of 3,4-Methylenedioxymethamphetamine (MDMA) . 3, 4-dihydroxyamphetamine (hydrochloride) is cytotoxic to rat hepatocytes. 3, 4-dihydroxyamphetamine (hydrochloride) is also used in the study of high blood pressure[1][2][3].
Product Specifications
CAS Number
828-06-8
Product Name Alternative
α-Methyldopamine (hydrochloride) ; α-MeDA (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
CC(N)CC1=CC(O)=C(O)C=C1.Cl
Molecular Formula
C9H14ClNO2
Molecular Weight
203.67
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Schwaninger AE, et al. Urinary excretion kinetics of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its phase I and phase II metabolites in humans following controlled MDMA administration. Clin Chem. 2011 Dec;57 (12) :1748-56. |[2]Carvalho M, et al. Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates. Arch Toxicol. 2004 Jan;78 (1) :16-24.|[3]Waldmeier P, et al. On the role of alpha-methyldopamine in the antihypertensive effect of alpha-methyldopa. Naunyn Schmiedebergs Arch Pharmacol. 1975;289 (3) :303-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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