Ethyl phenylglyoxylate-d5

Ethyl phenylglyoxylate-d5 (Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5) is the deuterium labeled Ethyl phenylglyoxylate (HY-W016618) . Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions[1][2][3].

Product Specifications

CAS Number

[1025892-26-5]

Product Name Alternative

Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5

UNSPSC

12352005

Target

Biochemical Assay Reagents; Carboxylesterase (CES) ; Drug Intermediate; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Smiles

[2H]C1=C([2H])C([2H])=C(C(C(OCC)=O)=O)C([2H])=C1[2H]

Molecular Formula

C10H5D5O3

Molecular Weight

183.22

References & Citations

[1]Shengkui Hu, et al. Photochemically Active Polymers Containing Pendant Ethyl Phenylglyoxylate. Macromolecules 1998, 31, 2, 322-327.|[2]Hu S, et al. Photoreduction of ethyl phenylglyoxylate. Journal of Photochemistry and Photobiology A: Chemistry, 1998, 114 (2) : 103-108.|[3]Berndt M C, et al. Ethyl phenylglyoxylate, a simultaneous inhibitor and substrate of chicken liver carboxylesterase (EC 3.1. 1.1) . Enzyme-catalyzed fragmentation of (E) -benzil monoxime O-2, 4-dinitrophenyl ether. Journal of the American Chemical Society, 1977, 99 (25) : 8334-8335.