Cicletanine (hydrochloride)

Cicletanine hydrochloride is an orally active Furopyridine-derivative antihypertensive agent. Cicletanine hydrochloride stimulates NO release. Cicletanine hydrochloride induces effective pulmonary vasodilation[1][2].

Product Specifications

CAS Number

[82747-56-6]

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Drug Derivative; NO Synthase

Related Pathways

Immunology/Inflammation; Others

Field of Research

Cardiovascular Disease

Smiles

ClC1=CC=C(C2OCC3=C(C(C)=NC=C32)O)C=C1.Cl

Molecular Formula

C14H13Cl2NO2

Molecular Weight

298.16

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

[1]Saadjian A, et al. Long-term effects of cicletanine on secondary pulmonary hypertension. J Cardiovasc Pharmacol. 1998 Mar;31 (3) :364-71.|[2]Kalinowski L, et al. Cicletanine stimulates nitric oxide release and scavenges superoxide in endothelial cells. J Cardiovasc Pharmacol. 2001 Jun;37 (6) :713-24.