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IMPDH-IN-2

IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity[1].

Product Specifications

CAS Number

31858-65-8

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IMPDH

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.95

Smiles

CC1=C(C(C/C=C(CCC(O)=O)\C)=C(C2=C1COC2=O)O)O

Molecular Formula

C16H18O6

Molecular Weight

306.31

Precautions

H302, H315, H319, H335

References & Citations

[1] Mitsuhashi S, et al. Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives. Bioorg Med Chem. 2010 Nov 15;18 (22) :8106-11.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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