4-Hydroxy valsartan

4-Hydroxy valsartan is a metabolite of Valsartan (HY-18204) . 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or whole blood collagen induced platelet aggregation. 4-Hydroxy valsartan has antiplatelet activity[1].

Product Specifications

CAS Number

[188259-69-0]

Product Name Alternative

Valeryl-4-hydroxyvalsartan; CGP 71580

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

O=C(N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)[C@@H](C(C)C)C(O)=O)CCC(C)O

Molecular Formula

C24H29N5O4

Molecular Weight

451.52

References & Citations

[1]Serebruany VL, et al. Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. J Cardiovasc Pharmacol. 2004 May;43 (5) :677-84.