4-Hydroxy valsartan
4-Hydroxy valsartan is a metabolite of Valsartan. 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or whole blood collagen induced platelet aggregation. 4-Hydroxy valsartan has antiplatelet activity[1].
Product Specifications
CAS Number
188259-69-0
Product Name Alternative
Valeryl-4-hydroxyvalsartan; CGP 71580
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C(N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)[C@@H](C(C)C)C(O)=O)CCC(C)O
Molecular Formula
C24H29N5O4
Molecular Weight
451.52
References & Citations
[1]Serebruany VL, et al. Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. J Cardiovasc Pharmacol. 2004 May;43 (5) :677-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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