Chlorido[N, N'-disalicylidene-1,2-phenylenediamine]iron (III)
Selected Variant
HY-W698255-01
Size: 5 mg
Chlorido[N, N'-disalicylidene-1,2-phenylenediamine]iron (III) generates lipid-based ROS and induce ferroptosis
Product Specifications
CAS Number
39916-28-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ferroptosis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
[Cl-][Fe+3]123[O-]C4=C(C=[N]1C5=C([N]2=CC6=C([O-]3)C=CC=C6)C=CC=C5)C=CC=C4
Molecular Formula
C20H14ClFeN2O2
Molecular Weight
405.64
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Jessica Sagasser, et al. A New Approach in Cancer Treatment: Discovery of Chlorido[ N, N'-disalicylidene-1,2-phenylenediamine]iron (III) Complexes as Ferroptosis Inducers. J Med Chem. 2019 Sep 12;62 (17) :8053-8061.|[2]Soo-Young Lee, et al. [FeIII (salophene) Cl], a potent iron salophene complex overcomes multiple drug resistance in lymphoma and leukemia cells. Leukemia Research 35 (2011) 387-393.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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