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5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindole-1,3-dione

5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione is a Thalidomide analogue featuring a hydroxy group, which is a versatile site for further derivitization. Thalidomide is an E3 ligase activator and promotes the ubiquitinylation of a given protein.

Product Specifications

CAS Number

2589697-74-3

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Purity

98.0

Smiles

CN1C(CCC(C1=O)N2C(C3=C(C2=O)C=C(C=C3)O)=O)=O

Molecular Formula

C14H12N2O5

Molecular Weight

288.26

Precautions

H302, H312, H332

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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