Zapotin

Zapotin is a member of the polymethoxyflavones, which are natural polyphenols from the group of flavonoid. Zapotin exhibits antidepressant, anticancer, antifungal, and antioxidant activity. Zapotin is a chemopreventive and chemotherapeutic agent. Zapotin can result in a reduction of large aberrant crypt foci in CF-1 mouse model. Zapotin inhibits autophagosome formation. Zapotin has inhibitory activity in mouse mammary organ culture with an IC50 of 50 µg/mL[1].

Product Specifications

CAS Number

[14813-19-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Biochemical Assay Reagents; Fungal; Reactive Oxygen Species (ROS)

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer; Infection; Metabolic Disease; Neurological Disease

Smiles

COC1=CC=C2OC(C3=C(C=CC=C3OC)OC)=CC(C2=C1OC)=O

Molecular Formula

C19H18O6

Molecular Weight

342.34

Precautions

P261-P280-P302+P352

References & Citations

[1]Strawa, J. W., et al., (2021) . Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes. International journal of molecular sciences, 22 (24), 13227.