Bamipine
Bamipine is a potent histamine H1-receptor antagonist. Bamipine exhibits moderate activity against Mycobacterium tuberculosis. Bamipine has a mild sedative effect[1][2].
Product Specifications
CAS Number
4945-47-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial; Histamine Receptor
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Infection; Neurological Disease
Smiles
CN1CCC(CC1)N(CC1=CC=CC=C1)C1=CC=CC=C1
Molecular Formula
C19H24N2
Molecular Weight
280.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Weis R, et al. Antimycobacterial and H1-antihistaminic activity of 2-substituted piperidine derivatives. Bioorg Med Chem. 2008 Dec 15;16 (24) :10326-31.|[2]Kountourelli JE, Markopoulou CK. A simultaneous analysis by high performance liquid chromatography of bamipine combined with tricyclic antidepressants and/or antipsychotics in dosage forms. Journal of liquid chromatography. 1991 Sep 1;14 (15) :2969-77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor
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