NR2F6 modulator-2
NR2F6 modulator-2 (Compound I) is an autorepressed orphan nuclear receptor NR2F6 (Nuclear Receptor subfamily 2 group F member 6) modulator. NR2F6 modulator-2 can inhibits the recruitment of the bio-NSD1 peptide with an IC50 of 2.0 equivalents of NR2F6. NR2F6 modulator-2 can be used for the researches of cancer and immunology[1].
Product Specifications
CAS Number
22978-55-8
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Orphan Nuclear Receptor
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
OC1=CC=C(NC(=O)C2=CC(=CC=C2Cl)[N+]([O-])=O)C=C1
Molecular Formula
C13H9ClN2O4
Molecular Weight
292.67
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Oerlemans GJM, et al. Structural Elucidation and Covalent Modulation of the Autorepressed Orphan Nuclear Receptor NR2F6. ACS Chem Biol. 2025 Sep 19;20 (9) :2308-2317.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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