Desmonomethylpromazine

Desmonomethylpromazine is the brain-penetrant demethylated metabolite of Promazine (HY-B1225A) . Desmonomethylpromazine can enter red blood cells and tissues through passive diffusion, distributes in tissues such as lung, liver, and kidney in rats[1][2].

Product Specifications

CAS Number

[2095-20-7]

UNSPSC

12352005

Hazard Statement

H315-H318-H335

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

CNCCCN1C2=C(C=CC=C2)SC3=C1C=CC=C3

Molecular Formula

C16H18N2S

Molecular Weight

270.39

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Daniel KRAPPMANN, et al. Selective inhibition of malt1 protease by phenothiazine derivatives. WO2013017637A1. 2013-02-07.|[2]Hu OY, et al. Stability, human blood distribution and rat tissue localization of promazine and desmonomethylpromazine. Biopharm Drug Dispos. 1989 Nov-Dec;10 (6) :537-48.