Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

10-Hydroxy-2-decenoic acid (Standard)

10-Hydroxy-2-decenoic acid (Standard) is an analytical standard for 10-Hydroxy-2-decenoic acid. This product is intended for research and analytical applications.10-Hydroxy-2-decenoic acid (10-HDA) is an orally active unsaturated medium-chain fatty acid with various physiological activities. 10-Hydroxy-2-decenoic acid induces ROS-mediated apoptosis in A549 cells. 10-Hydroxy-2-decenoic acid inhibits VEGF-induced angiogenesis in human venous endothelial cells. 10-Hydroxy-2-decenoic acid alleviates non-alcoholic fatty liver disease (NAFLD) by activating the AMPK-α signaling pathway. 10-Hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. 10-Hydroxy-2-decenoic acid is an antibiotic against many bacteria and fungi, such as Neurospora sitophila, molds and Staphylococcus aureus. 10-Hydroxy-2-decenoic acid has longevity-promoting effects in C. elegans. 10-Hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence[1][2][3][4][5][6][7][8][9][10].

Product Specifications

CAS Number

765-01-5

UNSPSC

12352211

Target

MTOR

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Smiles

O=C(O)/C=C/CCCCCCCO

Molecular Formula

C10H18O3

Molecular Weight

186.25

References & Citations

[1]Geng N, et al.10-hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence in male mice preclinically. Nat Commun. 2024 Sep 4;15 (1) :7712.|[2]TOWNSEND GF, et al. Studies on the in vitro antitumor activity of fatty acids. I. 10-Hydroxy-2-decenoic acid from royal jelly. Cancer Res. 1960 May;20:503-10.|[3]Tang M, et al. 10-Hydroxy-2-decenoic acid attenuates nonalcoholic fatty liver disease by activating AMPK-α signaling pathway. Biochem Pharmacol. 2025 Jan;231:116648. |[4]Han L, et al. 10-hydroxy-2-decenoic acid alleviates lipopolysaccharide-induced intestinal mucosal injury through anti-inflammatory, antioxidant, and gut microbiota modulation activities in chickens. Front Microbiol. 2023 Oct 17;14:1285299.|[5]Gao K, et al. Anti-Biofilm and Anti-Hemolysis Activities of 10-Hydroxy-2-decenoic Acid against Staphylococcus aureus. Molecules. 2022 Feb 22;27 (5) :1485.|[6]Gao K, et al. Anti-Biofilm and Anti-Hemolysis Activities of 10-Hydroxy-2-decenoic Acid against Staphylococcus aureus. Molecules. 2022 Feb 22;27 (5) :1485.|[7]BLUM MS, et al. 10-Hydroxy-delta 2-decenoic acid, an antibiotic found in royal jelly. Science. 1959 Aug 21;130 (3373) :452-3. |[8]Lin XM, et al. 10-HDA Induces ROS-Mediated Apoptosis in A549 Human Lung Cancer Cells by Regulating the MAPK, STAT3, NF-κB, and TGF-β1 Signaling Pathways. Biomed Res Int. 2020 Dec 8;2020:3042636|[9]Honda Y, et al. Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans. PLoS One. 2011;6 (8) :e23527.|[10]Tsuchiya Y, et al. The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. J Biol Chem. 2020 Aug 21;295 (34) :12224-12232.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human CCL5 Recombinant Rabbit monoclonal Antibody
HA725055 100 µL

Human CCL5 Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
Glucokinase (GCK) (NM_033508) Human Over-expression Lysate
LC403250 20 µg

Glucokinase (GCK) (NM_033508) Human Over-expression Lysate

Sign In for Pricing
View Details
Ubd (NM_023137) Mouse Tagged ORF Clone
MG201267 10 µg

Ubd (NM_023137) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
CYP2W1 (NM_017781) Human Recombinant Protein
TP306472 20 µg

CYP2W1 (NM_017781) Human Recombinant Protein

Sign In for Pricing
View Details
TMEM205 (142-151) Goat Polyclonal Antibody
AP22430PU-N 100 µg

TMEM205 (142-151) Goat Polyclonal Antibody

Sign In for Pricing
View Details
2-(2-Chloroethyl)-1-nitrosopyrrolidine
TRC-C478890-25MG 25 mg

2-(2-Chloroethyl)-1-nitrosopyrrolidine

Sign In for Pricing
View Details