14- (Fmoc-amino) -tetradecanoic acid
14- (Fmoc-amino) -tetradecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. 14- (Fmoc-amino) -tetradecanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Product Specifications
CAS Number
[1931109-55-5]
UNSPSC
12352005
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(O)CCCCCCCCCCCCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Molecular Formula
C29H39NO4
Molecular Weight
465.62
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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