3,4-Dibromo-Mal-PEG4-Acid
3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Product Specifications
CAS Number
[2434639-17-3]
UNSPSC
12352203
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
O=C(CCOCCOCCOCCOCCN1C(C(Br)=C(C1=O)Br)=O)O
Molecular Formula
C15H21Br2NO8
Molecular Weight
503.14
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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