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3,4-Dibromo-Mal-PEG4-Acid

3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.

Product Specifications

CAS Number

[2434639-17-3]

UNSPSC

12352203

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

O=C(CCOCCOCCOCCOCCN1C(C(Br)=C(C1=O)Br)=O)O

Molecular Formula

C15H21Br2NO8

Molecular Weight

503.14

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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