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DBCO-PEG4-Val-Ala-PAB

DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.

Product Specifications

CAS Number

[2348405-92-3]

UNSPSC

12352203

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC([C@@H](C(N[C@H](C(NC1=CC=C(C=C1)CO)=O)C)=O)NC(CCOCCOCCOCCOCCNC(CCC(N2CC3=C(C#CC4=C2C=CC=C4)C=CC=C3)=O)=O)=O)C

Molecular Formula

C45H57N5O10

Molecular Weight

827.96

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Curated Selection

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