P131
P131 is a PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain. P131 can degrade both wild-type and C481S mutant BTK with nanomolar potencies.
Product Specifications
CAS Number
[2360561-66-4]
UNSPSC
12352005
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
NC1=NC=NC2=C1C(C3=CC=C(C=C3)OC4=CC=CC=C4)=NN2[C@@H]5CCCN(C5)C(C6=CN(N=N6)CCOCCOCCOCCNC7=C8C(N(C(C8=CC=C7)=O)C9CCC(NC9=O)=O)=O)=O
Molecular Formula
C46H48N12O9
Molecular Weight
912.95
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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