12-Tridecenoic acid

12-Tridecenoic acid is a metabolite of intestinal flora, which can promote the expression of acetyl-CoA carboxylase α (ACC) and inhibit the expression of carnitine palmitoyltransferase 1A (CPT1A), thereby aggravating hepatic steatosis. 12-Tridecenoic acid aggravates hepatic steatosis by affecting the ACC-CPT1A axis[1].

Product Specifications

CAS Number

[6006-06-0]

UNSPSC

12352211

Hazard Statement

H302, H312, H332

Target

Acetyl-CoA Carboxylase; Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

95.0

Smiles

C=CCCCCCCCCCCC(O)=O

Molecular Formula

C13H24O2

Molecular Weight

212.33

Precautions

H302, H312, H332

References & Citations

[1]Xu R, et al. Gan-jiang-ling-zhu decoction improves steatohepatitis by regulating gut microbiota-mediated 12-tridecenoic acid inhibition. Front Pharmacol. 2024 Aug 23;15:1444561.