Cotinine N-β-D-Glucuronide

Cotinine N-β-D-Glucuronide is a glucuronide conjugate of the tobacco metabolite Cotinine (HY-B1178) . Cotinine N-β-D-Glucuronide is promising for research of tobacco carcinogen metabolism and cognitive function[1][2].

Product Specifications

CAS Number

[139427-57-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Purity

96.64

Smiles

O[C@H]1[C@H]([N+]2=CC=CC([C@H]3N(C(CC3)=O)C)=C2)O[C@@H]([C@H]([C@@H]1O)O)C([O-])=O

Molecular Formula

C16H20N2O7

Molecular Weight

352.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Dator R, et al. Metabolomics Profiles of Smokers from Two Ethnic Groups with Differing Lung Cancer Risk. Chem Res Toxicol. 2020 Aug 17;33 (8) :2087-2098.|[2]Huang C, et al. Urinary nicotine metabolites are associated with cognitive impairment among the elderly in southern China. Tob Induc Dis. 2023 Oct 4;21:123.