5β-Dihydroprogesterone
5β-Dihydroprogesterone (5βDHP) is the metabolite of Progesterone. 5β-Dihydroprogesterone binds to oxytocin receptor, reduces the Oxytocin (HY-17571) -induced calcium signal transduction, thereby exhibiting the tocolytic activity[1].
Product Specifications
CAS Number
128-23-4
Product Name Alternative
5βDHP
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Oxytocin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Purity
99.94
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](CC[C@]1([H])CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C(C)=O)C
Molecular Formula
C21H32O2
Molecular Weight
316.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Sheehan PM, et al., 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term. Mol Hum Reprod. 2005 Jul;11 (7) :495-501.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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