6-Phosphoglucono-δ-lactone
6-Phosphoglucono-δ-lactone (6-PGδL) is a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD) . 6-Phosphoglucono-δ-lactone is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP) . 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research[1][2].
Product Specifications
CAS Number
[2641-81-8]
Product Name Alternative
6-PGδL; 6-Phosphonoglucono-D-lactone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; PDI
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Cardiovascular Disease
Purity
99.0
Smiles
O=P(O)(O)OC[C@@H]1[C@H]([C@@H]([C@H](C(O1)=O)O)O)O
Molecular Formula
C6H11O9P
Molecular Weight
258.12
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
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