Juvenile hormone B 3 (mixture of diastereomers)

Juvenile hormone B 3 (Juvenile hormone III bisepoxide) (mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce) . Juvenile hormone B 3 can be used for insect lethality research[1][2].

Product Specifications

CAS Number

[120293-93-8]

Product Name Alternative

Juvenile hormone III bisepoxide; Juvenile hormone bisepoxide; JHB3

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

C-Met/HGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Others

Smiles

CC(C)(O1)[C@H]1CC[C@]2([C@@H](O2)CC/C(C)=C/C(OC)=O)C

Molecular Formula

C16H26O4

Molecular Weight

282.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Wen D, et al. Methyl farnesoate plays a dual role in regulating Drosophila metamorphosis. PLoS Genet. 2015 Mar 16;11 (3) :e1005038.|[2]Harshman LG, et al. Bioassays of compounds with potential juvenoid activity on Drosophila melanogaster: juvenile hormone III, bisepoxide juvenile hormone III and methyl farnesoates. J Insect Physiol. 2010 Oct;56 (10) :1465-70.