Carboxyphosphamide

Carboxyphosphamide is an inactive metabolite of the alkylating agent Cyclophosphamide (HY-17420) [1].

Product Specifications

CAS Number

[22788-18-7]

UNSPSC

12352211

Hazard Statement

H301, H319

Target

DNA Alkylator/Crosslinker

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

98.15

Smiles

O=C(CCOP(N)(N(CCCl)CCCl)=O)O

Molecular Formula

C7H15Cl2N2O4P

Molecular Weight

293.08

Precautions

H301, H319

References & Citations

[1]Manthey CL, et al. Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenases. Biochem Pharmacol. 1988 Jul 15;37 (14) :2781-90.