Thalidomide-5-methanol
Thalidomide-5-methanol is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-5-methanol can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[2825006-38-8]
UNSPSC
12352005
Hazard Statement
H302-H361
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)CO
Molecular Formula
C14H12N2O5
Molecular Weight
288.26
Precautions
P264-P270-P330-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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