Thalidomide-5-Br,6-F

Thalidomide-5-Br,6-F is a Thalidomide analogue. Thalidomide-5-Br,6-F is an activator of E3 ligase, which ubiquitinylates proteins for proteolysis. The structure may be further derivatized via substitution at fluorine or bromine.

Product Specifications

CAS Number

[2803445-69-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(F)C(Br)=C3)=O

Molecular Formula

C13H8BrFN2O4

Molecular Weight

355.12

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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