Nε- (Carboxyethyl) lysine
Nε- (Carboxyethyl) lysine is an advanced glycation end product (AGE) . Nε- (Carboxyethyl) lysine causes cross-linking between proteins, affects the structure and function of proteins, and leads to protein denaturation. Nε- (Carboxyethyl) lysine binds to RAGE receptors, affects cell signaling, regulates processes such as inflammatory response, cell proliferation and apoptosis. Nε- (Carboxyethyl) lysine affects glutamate transporter, reduces glutamate uptake and S100B protein secretion, affects neurotransmission in the nervous system, and exhibits diabetic-related neurotoxicity[1][2].
Product Specifications
CAS Number
5746-03-2
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
EAAT
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.9
Smiles
N[C@@H](CCCCNC(C(O)=O)C)C(O)=O
Molecular Formula
C9H18N2O4
Molecular Weight
218.25
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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