Chlorotris (triphenylphosphine) copper

Chlorotris (triphenylphosphine) copper (CuCl (TPP) ₃) is a DNA-targeted metal complex. Chlorotris (triphenylphosphine) copper involves non-covalent interactions (such as groove binding mode) through the copper (I) center to affect DNA function, showing inhibitory activity against bacteria, fungi, and tumor cells. Chlorotris (triphenylphosphine) copper is promising for research of antibacterial, antitumor, and antioxidant agents[1].

Product Specifications

CAS Number

[15709-76-9]

Product Name Alternative

CuCl (TPP) 3

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Bacterial; DNA Stain; Fungal

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Cancer; Infection

Purity

98.0

Smiles

[Cl-][Cu+]([P](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)([P](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)[P](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9

Molecular Formula

C54H45ClCuP3

Molecular Weight

885.86

Precautions

H315, H319

References & Citations

[1]Khan S I, et al. Mononuclear copper (I) complexes with triphenylphosphine and N, N′-disubstituted thioureas: synthesis, characterization, and biological evaluation[J]. Journal of Coordination Chemistry, 2018, 71 (24) : 4086-4108.