Dimethyl diacetyl cystinate
Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor. Dimethyl diacetyl cystinate shifts the intracellular redox balance toward the oxidized state by increasing intracellular oxidized glutathione (GSSG) content, competitively blocking the binding of activated NF-κB to DNA, thereby inhibiting the production of inflammatory factors such as IL-1κ. Dimethyl diacetyl cystinate is promising for research of UVB-induced skin inflammation and related oxidative stress diseases[1].
Product Specifications
CAS Number
[32381-28-5]
Product Name Alternative
DACDM
UNSPSC
12352211
Hazard Statement
H302-H315-H319
Target
Interleukin Related; NF-κB
Related Pathways
Immunology/Inflammation; NF-κB
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
CC(N[C@H](C(OC)=O)CSSC[C@H](NC(C)=O)C(OC)=O)=O
Molecular Formula
C12H20N2O6S2
Molecular Weight
352.43
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P501
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W550315/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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