Thalidomide-4-Br,7-F
Thalidomide-4-Br,7-F is an E3 ligase activator featuring a bromine and a fluorine. E3 ligase is a protein that marks other proteins for proteolytic destruction by labeling them with ubiquitin. Both halogens may be substituted for further derivitization.
Product Specifications
CAS Number
[2740657-30-9]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C(F)=CC=C3Br)=O
Molecular Formula
C13H8BrFN2O4
Molecular Weight
355.12
Precautions
P264-P280-P302+P352-P362+P364
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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