(S) -Thalidomide-5-OH
(S) -Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S) -Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
172333-29-8
UNSPSC
12352005
Hazard Statement
H302-H361-H373
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1N(C(=O)C=2C1=CC(O)=CC2)[C@@H]3C(=O)NC(=O)CC3
Molecular Formula
C13H10N2O5
Molecular Weight
274.23
Precautions
P264-P270-P280-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
Cereblon
Frequently Asked Questions
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