Thalidomide-4-F,5-Br
Thalidomide-4-F,5-Br is a Thalidomide analogue. Thalidomide recruits E3 ligase for the ubiquitinylation and subsequent proteolysis of a target protein. This molecule may be derivatized through substitution at fluorine or bromine.
Product Specifications
CAS Number
[2740657-28-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Purity
99.37
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(C(F)=C3C2=O)Br)=O)=O
Molecular Formula
C13H8BrFN2O4
Molecular Weight
355.12
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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