Thalidomide-4-F,5-Br

Thalidomide-4-F,5-Br is a Thalidomide analogue. Thalidomide recruits E3 ligase for the ubiquitinylation and subsequent proteolysis of a target protein. This molecule may be derivatized through substitution at fluorine or bromine.

Product Specifications

CAS Number

[2740657-28-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Purity

99.37

Smiles

O=C1NC(C(CC1)N2C(C3=CC=C(C(F)=C3C2=O)Br)=O)=O

Molecular Formula

C13H8BrFN2O4

Molecular Weight

355.12

Precautions

H302, H315, H319, H335

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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